Treatment of essential hypertension: The usually effective dose is 40mg once daily. Some patients may already benefit at a daily dose of 20mg. In cases where the target blood pressure is not achieved, the dose of Teleshal can be increased to a maximum of 80mg once daily. Cardiovascular prevention: The recommended dose is 80mg once daily. It is not known whether doses lower than 80mg of Teleshal are effective in reducing cardiovascular morbidity.